Dated: Oct 05, 2022
Publication Name: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
Citations : A novel “dual-locked” fluorescent probe for ONOO– and viscosity enables serum-based rapid disease screening
Peroxynitrite (ONOO–) plays important roles in the progression of important disease such as inflammation, cancer, and diabetes, which made it an attractable target for biosensor development. However, to detect ONOO– solely is highly dependent on the sensitivity of the detection method and may be disturbed by unwillingly false-positive signal. Cellular viscosity is an important microenvironmental parameter and its abnormal changes are closely related to diseases such as diabetes and cancer.
Contributors: Baotang Shi, Huiling Wang, Xingxia Wan, Yu Guo, Shi-Yu Liu, Quan Gong