Customer Story: Allegheny College

Allegheny College uses our Axon patch-clamp instruments to investigate how amyloid beta peptide block ion channels in Alzheimer's disease

Dr. Lauren French is working with undergraduate students at Allegheny College to find out how the amyloid beta peptide implicated in Alzheimer’s disease pathology inhibits a calcium-activated potassium channels. This channel interaction was reported by Yamamoto et al. (2011), and the students in her lab are investigating it using the Xenopus oocyte expression system.