Dated: Jan 12, 2021
Publication Name: Molecular Devices
Citations : Evaluation of mitochondrial integrity and mitochondria membrane potential using automated cell imaging and analysis
Mitochondrial function, a key indicator of cell health, can be assessed by monitoring changes in mitochondrial membrane potential (MMP)1,2. Mitochondrial depolarization is an early signal for hypoxic damage or oxidative stress. Cationic fluorescent dyes are commonly used tools to assess MMP. We performed a short-term (60 min) compound treatment with two known inhibitors of oxidative phosphorylation, Antimycin A and CCCP.
Contributors: Matthew Hammer, Oksana Sirenko