Neurotoxicity

While there are many ways to test for neurotoxicity, most current methods are simplistic and do not accurately reflect the complex processes that occur in the body. Therefore, there is an urgent need to develop more predictive in vitro assays that can screen larger sets of compounds with the potential for neurotoxicity.

Learn more about using induced pluripotent stem cell-based neurite outgrowth assays, which can be used to assess neuronal development:

• Functional and Mechanistic Neurotoxicity Profiling Using Human iPSC-Derived Neural 3D Cultures
• Neurite Outgrowth in Human Induced Pluripotent Stem Cell-Derived Neurons as a High-Throughput Screen for Developmental Neurotoxicity or Neurotoxicity
• Functional evaluation of neurotoxic and neuroactive compound effects in iPSC-derived 3D neural co-cultures
• Assessment of neurotoxicity and neuronal development using induced pluripotent stem cell-based neurite outgrowth assay
• Calcium flux assay for in vitro neurotoxicity studies and drug screening
• In vitro platform for high-throughput screening of neurons enables automation of neurotoxicity assays
• AI-based analysis of complex biological phenotypes
• High-content screening of neuronal toxicity using iPSC-derived human neurons