Dated: Mar 03, 2020
Publication Name: International Immunopharmacology
Citations : Parallel comparison of three methodologies for measuring functional C1-inhibitor in Hereditary angioedema patients
Hereditary angioedema (HAE) types I and II are characterized by functional C1 inhibitor (fC1-INH) deficiency which results in bradykinin overproduction. Sensitive, specific and robust methods to quantitate fC1-INH in human samples are required for diagnosing HAE and/or to measure pharmacodynamic activity of C1-INH drugs in clinical studies.
Contributors: Archana Kapoor, Brijesh K. Garg, Zhiwei Zhou, Peng Lu, Priya S.Chockalingam