Dated: Oct 05, 2022
Publication Name: Antioxidants & Redox Signaling
Citations : Trisomy 21 increases microtubules and disrupts centriolar satellite localization
Researchers investigated how the chromosome 21-resident gene Pericentrin (PCNT) imbalances disrupt cilia. Single-cell clones were plated by manually seeding one cell into each well of 96-well plates. The CloneSelect Imager was used to select wells with a single colony.
Contributors: Bailey L. McCurdy, Cayla E. Jewett, Alexander J. Stemm-Wolf, Huy Nguyen Duc, Molishree Joshi, Joaquin M. Espinosa, Rytis Prekeris, and Chad G. Pearson