University of Geneva uses the FlexStation 3 and SpectraMax readers for assay development and screening
COMPANY/UNIVERSITY
University of Geneva, Readers, Assay Development and Screening Unit, Faculty of Medicine
TEAM MEMBERS
M. Yves Camet, Researcher
PRODUCTS USED
SpectraMax Paradigm Multi-Mode Microplate Reader
FlexStation 3 Multi-Mode Microplate Reader
SpectraMax L Microplate Reader
The Challenge
The Solution
To support this vital work, researchers use a variety of state-of-the-art microplate readers, including: the FlexStation® 3 Multi-Mode Microplate Reader for ion channel assays such as membrane potential or calcium assays, the SpectraMax® L Microplate Reader for all luciferase-based assays, the SpectraMax® Paradigm Multi-Mode Microplate Reader for a wide range of other assays such as ELISA, cytotoxicity, Bradford, cell viability assays, etc.
Two of these readers are equipped with a system of injection which allows scientists to measure several wells simultaneously in kinetic mode. By analysing all their data in the SoftMax® Pro Data Acquisition and Analysis Software, Yves is able to provide support for the calculation of pharmacological parameters such as IC50, Emax, Km, Kd, etc.
SpectraMax L Microplate Reader
FlexStation 3 Multi-Mode Microplate Reader
SpectraMax Paradigm Multi-Mode Microplate Reader
Products Used
With advanced dual optical systems operating above and below your microplates, the FlexStation® 3 Reader measures absorbance, fluorescence intensity, fluorescence polarization, luminescence, and time-resolved fluorescence. But that's just the beginning, because this incredible benchtop system integrates multi-mode microplate optics with precision, programmable liquid handling for perfectly timed, automated biochemical and cell-based assays. The FlexStation 3 Reader requires that you give up nothing in assay design, because it adds your assay reagents from a 96- or 384-well source plate.
Pave the pathway to your future with the SpectraMax® L Microplate Luminometer. Measure flash and glow assays, including dual luciferase reporter gene, G protein-coupled receptor (GPCR) via aequorin, bioluminescence resonance energy transfer (BRET), and acridinium ester flash assays, in both 96- and 384-well plates. When you're ready to scale up, the SpectraMax L Reader can give you up to a six-fold increase in throughput with multi-channel configuration upgrade options.
Future-proof your lab with the SpectraMax® Paradigm® Multi-Mode Microplate Reader. Get the system that delivers the data you need today, and when you need more, transform your reader with a detection-mode addition upgrade that takes less than two minutes. The SpectraMax Paradigm reader can do absorbance, fluorescence, time-resolved fluorescence (including HTRF), fluorescence polarization, AlphaScreen®, AlphaLISA®, and luminescence measurements. Detection cartridge modularity allows you to configure the system to meet your current needs, while providing flexibility to address future applications.